Using Dess-Martin Periodinane (DMP)
Using Swern Oxidation
Using PDC
Using PCC
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- Acid to Alcohol (Acid activation & NaBH4 reduction)
- Acid to Alcohol using NaBH4, I2
- Acid to Amide (acid anhydride, followed by amine)
- Acid to Amide (acid chloride, followed by amine)
- Acid to Amide (Esterification, followed by amine)
- Acid to Ester (Fischer Esterification)
- Acid to Ester (SOCl2 & alcohol)
- Acid to Ester (Steglich Esterification) - for t-butyl ester
- Acid to Ester [(COCl)2 & alcohol]
- Acid to Ester using Me2SO4 (for methyl ester)
- Acid to Ester using MeI, base (for methyl ester)
- Acid to Ester using Mitsunobu reaction
- Acid-Amine Coupling
- Acid-Amine Coupling using BOP
- Acid-Amine Coupling using DCC
- Acid-Amine Coupling using EDCI
- Acid-Amine Coupling using HATU
- Acid-Amine Coupling using HBTU
- Acid-Amine Coupling using Mukaiyama Reagent
- Acid-Amine Coupling using NHS Esters
- Acid-Amine Coupling using PyBOP
- Acid-Amine Coupling using T3P
- Acid-Amine Coupling using TBTU
- Acid-Amine Coupling using TSTU
- Alcohol to Aldehyde/Ketone using Corey-Kim Oxidation (DMSO, NCS)
- Alcohol to Aldehyde/Ketone using Dess-Martin Periodinane (DMP)
- Alcohol to Aldehyde/Ketone using Manganese Dioxide
- Alcohol to Aldehyde/Ketone using Parikh–Doering oxidation (DMSO, py.SO3)
- Alcohol to Aldehyde/Ketone using PCC (Pyridinium Chlorochromate)
- Alcohol to Aldehyde/Ketone using PDC (Pyridinium Dichromate)
- Alcohol to Aldehyde/Ketone using Pfitzner-Moffatt Oxidation
- Alcohol to Aldehyde/Ketone using Swern Oxidation
- Alcohol to Aldehyde/Ketone using Swern Oxidation variant (DMSO, TFAA)
- Alcohol to Azide using DPPA
- Alcohol to Azide using Mitsunobu reaction
- Alcohol to Bromide using HBr
- Alcohol to Bromide/Chloride using Appel reaction
- Alcohol to Carboxylic acid using Jones Reagent
- Alcohol to Carboxylic acid using NaClO, TEMPO
- Alcohol to Carboxylic acid using NMO, TPAP
- Alcohol to Chloride using Cyanuric chloride
- Alcohol to Chloride using Thionyl Chloride
- Alcohol to Ester using Fischer Esterification
- Alcohol to Ester using Steglich Esterification
- Alcohol to Ether using Mitsunobu reaction
- Alcohol to Ether using Williamson synthesis (O-Alkylation)
- Alcohol to Fluoro using DAST
- Alcohol to Iodide using Appel reaction
- Alcohol to Mesylate using MsCl, base
- Alcohol to Methylene (Deoxygenation) using Et3SiH, TFA
- Alcohol to Tosylate using Tosyl Cl, base
- Alcohol to Triflate using Tf2O, base
- Aldehyde to Alcohol using DIBAL-H reduction
- Aldehyde to Alcohol using NaBH4 reduction
- Aldehyde/Ketone to Alkene (Schlosser Modification of Wittig reaction)
- Aldehyde/Ketone to Alkene (Tebbe Olefination)
- Aldehyde/Ketone to Alkene (Wittig & Wittig-Horner reaction)
- Aldehyde/Ketone to Alkyne (Corey-Fuchs reaction & n-BuLi)
- Aldehyde/Ketone to Difluoro using DAST
- Aldehyde/Ketone to Difluoro using Deoxofluor
- Amide hydrolysis under basic condition
- BH3.Me2S (BMS reduction) reduction of Acids & Amides
- BH3.THF (Borane THF) reduction of Acids & Amides
- Buchwald-Hartwig Coupling
- C-C Bond Formation
- Cross-Coupling Reactions
- Cross-Coupling Reactions - Back-up details
- Deoxygenation of Aldehyde/Ketone (Clemmensen reduction)
- Deoxygenation of Aldehyde/Ketone (Thioacetal & reduction)
- Deoxygenation of Aldehyde/Ketone (Wolff-Kishner reduction)
- Ester Hydrolysis under acidic condition
- Ester hydrolysis under basic condition
- Ester to Acid (Reduction to Alcohol & Oxidation to aldehyde)
- Ester to Alcohol using DIBAL-H
- Ester to Alcohol using LiBH4
- Ester to Alcohol using NaBH4
- Ester to Aldehyde using DIBAL-H
- Functional Group Transformations
- Functional Group Transformations - Back-up details
- General Organic Chemistry
- Green Chemistry
- Heck Coupling
- LiAlH4 or LAH reduction of Acids, Esters & Amides
- Name Reactions
- Name Reagents
- Negishi Coupling
- Nitrile to Acid using acidic condition
- Nitrile to Acid using Basic condition
- Nitrile to Aldehyde using DIBAL-H
- Nitrile to Amide using UHP (Urea-Hydrogen peroxide)
- Nitrile to Amine (LiAlH4 or LAH reduction)
- Nitrile to Amine using Pd/C, H2
- Nitrile to Amine using Raney Ni, H2
- Nitrile to Ester using Pinner reaction
- Other details for website
- Page template
- Practical procedures & protocols for Organic Chemists
- Practical procedures & protocols for Organic Chemists - Back-up details
- Process Development
- Protecting Groups
- SNAr reaction - Cl displacement
- SNAr reaction - F displacement
- Sonogashira Coupling
- Stille Coupling
- Suzuki-Miyaura Coupling
- Test page
- Ullmann Coupling & other Cu Catalyzed reactions